Given the history of malware attacks through Excel and other macros, among other methods, I can see blocking changes to Excel registration could possibly be a viable method to block those types of infections. This was true even trying direct registry modifications (regedit)! I have 35 years experience in IT myself and was working directly with levels 1, 2, and 3 Microsoft technical support both over the phone and with webshare over a five day period. No method of assigning Excel as an app to those file types worked or even appeared to remain in force following the attempted assignment. xlsx type files however you would get the ".no default application." error message. Excel also worked just fine, as long as you called it directly. Office Home and Student 2016 appeared to install correctly (about 6 or 7 times during various attempts after a number of uninstalls, repairs, incense burning and animal sacrifices) and Word had no problems at all. So what does "Allow xxx to make changes to your computer" Yes actually do? It even blocked changing the registry directly through regedit!. It would be nice if Webroot informed you when it blocks a registry or associated app change from taking place. we finally disabled Webroot and voila, Excel can now be assigned as the app for these file types. Six hours of Microsoft support (no exageration) later, reinstalling Office, repairing Windows, etc., etc. xlsx file extensions so, while calling Excel directly, you can open spreadsheets and save new ones, but you cannot open those files directly and have Windows 10 recogise it is associated to Excel-you get an error saying there is no default program for that type of file. This prevents Excel being set up as an app associated with. I turns out that even when responding Yes to allow the install to make changes to the computer, Webroot prevents any changes to Excel's registry entries and doesn't inform you that it blocked the changes needed in the install. This is probably the last place someone with this problem will look, but I've just gone through Hell trying to install Microsoft Office 2016.
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